Start With the Obvious Before You Start With the Interesting
Something changed, and the patch you had working two hours ago is now a mess. Before reaching for an oscilloscope, work through the candidates in order of how often they actually cause the problem.
Signal loading is the first suspect. Every module has an output impedance and every downstream input has an input impedance; when you split one output across three or four inputs, you are forming a voltage divider, and the driven signal drops. A VCO pitch output that looked fine driving one oscillator will sag measurably when you parallel it to three VCOs without a buffered multiple in the chain. The symptom is usually pitch that is flat across the whole keyboard range rather than drifting at one end — 1V/oct calibration is doing the right thing, but it is working with a reduced voltage swing. Add a buffered multiple and recheck.
Ground loops are second. They appear when your case ground and some external piece of equipment — an effects pedal, an audio interface running on its own wall-wart — share a ground path through your audio cables that differs in potential from the shared chassis ground. The result is usually a fifty- or sixty-hertz hum sitting underneath the patch, most audible in quiet passages. Unplug external gear one piece at a time. If the hum disappears when you remove a specific cable, you have found the loop. The fix is a galvanic isolation transformer on the audio output, not a frantic rerouting of your patch.
